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Certain medications The following drugs can reduce levels of vitamin B12 in your body: Antibiotics -- long-term use can lower vitamin B levels generally Anti-seizure drugs Chemotherapy medicines, especially methotrexate Drugs used to reduce stomach acid, like H2 blockers (Pepcid AC, Tagamet, Zantac) and proton pump inhibitors (Nexium, Prevacid, Prilosec) Metformin (Glucophage) -- taken for diabetes Colchicine -- taken for gout Some cholesterol-lowering medications Other causes You're over 65

Rhonda Patrick adds: "NAD+ precursors like NMN increase levels, aiding DNA repair and energykey for anti-aging."[34] She suggests stacking with NNMT inhibitors for sustained effects

Alternativement, 1000mcg SC/MC peuvent tre administrs chaque jour pendant 2-7 jours, suivis d'un traitement d'entretien

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Others cycle it (e.g., 12 weeks on, 4 weeks off) or use it strategically during periods when metabolic support is needed (fat loss phases, aging, etc.)