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On top of the already discussed benefits for energy levels and combating stress, taking vitamin B12 on an empty stomach will aid absorption by creating an acidic environment the same goes for all nutrients that are not fat-soluble

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The recommended B12 dosage is as follows: Men over 14 years of age should consume 2.4 mcg daily Women over 14 years of age should also consume 2.4 mcg daily Pregnant Women should consume 2.6 mcg daily Lactating Women should consume 2.8 mcg daily Be sure to discuss your interest in B12 with a medical professional prior to beginning any supplementation

10.1038/373699a0 Nature 161 SchultzJ

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