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Viral binding/attachment to human cell surface receptors (CSRs) The virulent outcome of a SARS-CoV-2 infection depends on (i) binding/interaction of viral S-protein with human cell surface receptors (CSR) and (ii) priming of S-protein by human cellular proteases 54,55

Tirzepatide exerts its therapeutic effects through dual agonism of two key incretin receptors: the GIPR and the GLP-1R

Laraia BA, Adler NE, Coleman-Phox K, Vieten C, Mellin L, Kristeller JL, Thomas M, Stotland NE, Lustig RH , Dallman MF, Hecht FM, Bush NR, de Groat CL, Epel E

This effect is linked to activating a specific estrogen receptor (ER-alpha) in the brain

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This age-related decline correlates with reduced tissue repair capacity