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This anatomical feature partially explains how peripherally administered GLP-1 medications exert central effects despite limited overall brain penetration

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A new paper in the brings much-needed clarity: - (FFM) represents everything in the body except fat at the molecular level (LM) is synonymous with FFM but not with lean soft tissue (LST) belongs to the tissueorgan level and should not be confused with FFM or LST The authors call for standardised definitions across devices and studies By separating these concepts, clinicians and researchers can better interpret body-composition data, monitor muscle health during weight loss, and tailor interventions more precisely

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Some patients eventually decide to discontinue Ozempic or Wegovy