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More recently, another microbial product, p-cresol, a glucuronide, has been found to decrease permeability of the BBB in vitro and has protective effects over LPS induced BBB disruption in mice [156]

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The phenyl-substituted acetohydrazide 43 (Figure 30) exhibited the best COX-2 selectivity, although it was lower than that of celecoxib

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In this context, analytical methods such as HPLC peptide analysis and LC-MS verification can help evaluate purity, identity, molecular characteristics, and research material consistency