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The LEADER trial demonstrated that liraglutide significantly reduced the risk of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke
Patients should understand the difference between expected cold sensitivity and symptoms suggesting thyroid dysfunction, anemia, or other metabolic disorders that require investigation and management
tirzepatide in REDEFINE 4 (23% vs
In the 2021 STEP-1 trial (1,961 adults with obesity or overweight), participants receiving semaglutide plus lifestyle intervention experienced a 14.9% mean weight loss after 68 weeks, while those on placebo lost only 2.4%
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