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In a study published in JAMA, 26.2% of patients had discontinued GLP-1 therapy at 3 months, and 30.8% and 36.5 % had discontinued it at 6 and 12 months

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The development of anti-evolocumab antibodies was not detected in clinical trials of pediatric patients treated with REPATHA

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Third, and perhaps most importantly, self-administration removes the clinical feedback loop

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