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The characteristics of the included studies can be summarized using the population, intervention, comparison, and outcomes (PICO) model as follows: P: Patients with a confirmed diagnosis of any cancer type I: SFN as a primary or synergistic agent for cancer management

Reduced systemic inflammation Modulates NF-B signaling to lower inflammatory cytokine activity

Hope M, Saxby TS

Improved Cognitive Function and Memory : Regular B12 injections can enhance cognitive abilities, improve memory and protect against age-related decline

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