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Mechanism of Action How Dihexa activates the HGF/c-Met pathway to promote synaptogenesis, dendritic spine formation, and long-term potentiation

In addition to the nanoparticles being able to affect M2 TAMs in TME mentioned above, inhibition of lactate production can also effectively restore immunosuppressive TME based on the fact that cancer cells continue to produce lactate through aerobic glycolysis thereby promoting TAMs polarization to the M2 phenotype

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YAP/TAZ One of the main risk factor for gastric cancer is Helicobacter pylori infection