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Some of its been in mice or rats, but they sort of have, you know, many have gone in and put together and extrapolated, well, if this is the mechanism of action and this is how it works, and we know these receptors are present in humans, then it would seem, you know, You know, appropriate to attempt to see if this would be helpful for this

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Cells in WT mouse islets presented a similar distribution of mitochondrial morphologies as in INS-1 832/3 cells, with mitochondria primarily hyperfused or tubular under vehicle conditions but remodelling towards a more fragmented phenotype following exendin-4 exposure (Fig