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The presence of this imbalance can significantly impact various physiological processes, resulting in a diverse array of health complications ( Endogenous antioxidant systems control ROS, chemically reactive molecules produced by cellular metabolism ( Oxidative stress caused by an imbalance in the adrenal hormones has many effects

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Metformin) with diagnosis of type 2 diabetes Documented history of lifestyle intervention Quarterly clinical review to assess improvement (weight loss or A1C) Discontinuation if there is no measurable improvement after 6 months 3

doi: 10.3390/antiox10111702

Clinical and biochemical parameters were assessed at baseline and 6 months, with additional weight assessments at 3 months