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In trials both components are titrated weekly in parallel toward 2.4 mg + 2.4 mg once weekly over roughly 16 weeks

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For this reason, medications that are often broken down in the digestive tract can reach their target tissues while remaining intact

Brown pigmentation on the tongue can represent physiological variation (particularly in individuals with darker skin tones), benign conditions, systemic disease markers, or - less commonly - something requiring more urgent evaluation

Obesity in asthma: more neutrophilic inflammation as a possible explanation for a reduced treatment response

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