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Therefore, GLP-1 should not induce hypoglycemia when administered alone or with other antidiabetic agents that do not cause hypoglycemia, such as metformin (MET), thiazolidinediones (TZDs) and alpha-glucosidase inhibitors (AGIs)

It increases the risk of heart disease, high blood pressure, colon cancer, and type 2 diabetes

The practical fix: protein-first meals at scheduled times, 1.2-1.6 g per kg body weight daily, with a calorie floor of about 1200-1400 for women and 1500-1800 for men

Legal and Regulatory Considerations FDA Stance on Compounded GLP-1 Medications The FDA has expressed concerns about the safety of compounded semaglutide products

But its not magic

Semaglutide : Stimulates only the GLP-1 receptor, promoting insulin release, lowering blood sugar, and reducing appetite