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Avastin is currently approved by the FDA for metastatic cancer (cancer that has spread to other parts of the body)

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Pharmacokinetic Profiles of Available Agents The pharmacokinetic diversity amongst GLP-1 RAs has important implications for perioperative decision-making (Table 1)

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These findings confirm that while the GLP-1 RAs do not materially increase rare adverse events such as pancreatitis and severe hypoglycaemia, gastrointestinal side effects represent a predictable and clinically relevant class effect that often limits tolerability

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