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The MHRA-approved dosing schedule involves gradual titration, starting at 0.25 mg once weekly for 4 weeks, then increasing to 0.5 mg once weekly, with further increases to 1 mg or 2 mg possible after at least 4 weeks at each dose level

DOI: 10.3389/fimmu.2023.1143548

A patient considering a GLP-1 drug should be able to answer these questions honestly before starting: Has a qualified endocrinologist or physician evaluated my overall metabolic health, not just my weight

specific study formulations fall outside the scope of this discussion

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1 The primary goal of antidepressants is to manage the patients mental health symptoms, but a rapid weight gain could prove problematic, especially if the person is already overweight at the beginning of treatment