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Pharmacogenetic considerations for acute lymphoblastic leukemia therapies

BloodBrain Barrier, BloodCerebrospinal Fluid Barrier, and Neurovascular Unit The mammalian brain is separated from the general circulation system by the BBB, which is localized in the brain capillaries and pia-subarachnoid membranes, and the BCB localized in the choroid plexus of the brain ventricles

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