One study evaluated 549 healthy women who were post-menopause
Mycelium plugs or pure fresh mycelia were collected from fresh mycelia growing on PDA plates or cultured in Potato Dextrose Broth (PDB) for 2 d, inoculated onto plant leaves, and maintained at high humidity
The primary molecular actions relevant to skin are: modulation of TGF- signaling (upregulating TGF-1 for collagen I/III synthesis while suppressing TGF-2 to prevent scarring), decorin upregulation for orderly collagen fibril assembly, MMP suppression paired with TIMP upregulation to preserve ECM integrity, and copper-dependent lysyl oxidase activation for collagen crosslinking
Biofactors 9, 267272.10.1002/biof.5520090223 246 ShultsC
It binds to toxins, heavy metals, and waste products, making them water-soluble so they can be excreted through urine or bile
Zinc offers anti-inflammatory properties to help soothe swollen or itchy skin