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It is found in the mitochondria (powerhouses of cells) where it facilitates fat metabolism and energy production

Puede usarse: En monoterapia , cuando la metformina no es tolerada o est contraindicada

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The intake of LC lowers the intramitochondrial acetyl-CoA to free CoA ratio, which promotes pyruvate dehydrogenase activity and glucose oxidation

The importance of this antioxidant pathway is illustrated in Nrf2 knockout mice in which lung neutrophil inflammation and pulmonary emphysema were evident as early as 8 weeks after cigarette smoke exposure, whereas wild-type mice showed no lung changes at 16 weeks

48 House Armed Services Committee (HASC) Press Release, HASC Leadership Announces Bipartisan Defense Business Panel , September 12, 2011