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Dahnhardt et al, in 2024, conducted a pilot study in Germany investigating the effects of a 12-week administration of a custom nutraceutical supplement (given daily) that contained special collagen peptides on the structural properties of the collagen fiber network in human skin [47]

In PCOS, oxidative stress contributes to: Hormonal disruption Insulin resistance Inflammation Poor skin recovery Pigmentation flare-ups Glutathione helps by: Reducing free radical damage Supporting cellular repair Calming stress-driven melanin activity This is why skin issues in PCOS often improve after internal balance improves , not before

It inhibits histone deacetylase (HDAC) and modulates DNA methyltransferase (DNMT) activity

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