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It is commonly used to target areas like the abdomen, thighs, and arms

[5] Avoid B12 shots if: You have kidney or liver disease

Further, a secondary analysis of a trial in women at high risk for or with existing cardiovascular disease reported that high-dose supplemental B-vitamins (1 mg/day of vitamin B 12 , 50 mg/day of vitamin B6, and 2.5 mg/day of folic acid) for 7.3 years had no effect on risk of non-vertebral fractures (122)

(yes, different syringe) He tested very low B12 before supplementing (though barely in range) and is having some cognitive decline, so this works for us

For example, a 2019 study of over 9,000 adults found people with obesity had lower blood levels of vitamin B12 (8)

The researchers noted that patients who were "responders" required significantly higher doses than standard deficiency protocols to maintain their clinical improvements, suggesting a high cellular demand for the nutrient in the face of chronic oxidative stress