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12 Patients with 4-hour postingestion plasma acetaminophen levels above the possible line on the Rumack-Matthew nomogram must be admitted as hospital inpatients for treatment with the antidote, NAC, and to enable ongoing clinical evaluation for signs of hepatotoxicity

This leftover volume is a built-in buffer, not a usable dose, he continued

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The powder should be kept in places with low humidity to keep it from sticking together and to keep the phospholipid coating intact

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