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Common adverse effects such as nausea, vomiting, diarrhoea, or constipation typically improve within 2 to 4 weeks after stopping

The more recent Phase 3 TRIUMPH 4 trial showed even more impressive results, with participants losing up to 28.7% of their starting weight over 68 weeks

FM-P acknowledges the support from ANID FONDECYT grant No

Intracellular Zn(2+) signaling facilitates mossy fiber input-induced heterosynaptic potentiation of direct cortical inputs in hippocampal CA3 pyramidal cells

Common gastrointestinal effects include nausea, constipation, diarrhoea, and bloating, but stool colour changes are not listed as adverse effects in UK SmPCs