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Bodyweight decreased dose-dependently with retatrutide at 36 weeks by up to 16.94% for the 12 mg escalation group, compared to 3.00% with placebo and 2.02% with 1.5 mg of dulaglutide

Nature 477, 330334

Weightliftings Risky New Trend: A Case Series of 41 Insulin Users

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Three months after stopping Zepbound, study participants who underwent the Fractyl procedure generally held their weight steady or continued to lose weight, while those who received a sham treatment saw the number on their scales climb steadily upward