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When doses are introduced too quickly or increased too aggressively, the cumulative effect on stomach function can exceed your body's adaptive capacity, leading to nausea, bloating, vomiting, or constipation

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Yang, H., Choi, E., Park, E., Na, E., Chung, S

A three-year obesity and prediabetes trial found that LIR 3 mg can improve health benefits in reducing the diabetes risk of patients with obesity and prediabetes (91)