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Some anesthesiologists are now choosing to avoid nitrous oxide usage in individuals with known MTHFR mutations (19) and instead utilize other inhaled anesthetics such as sevoflurane

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Potential side effects include: Nausea or mild stomach upset Fatigue Headache Gas or changes in bowel movements Low blood sugar (rare) If side effects are prolonged or difficult to tolerate, providers may recommend alternatives such as tirzepatide, which can have a different side effect profile.

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10 , e9355 (2018)