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It enters intestinal cells directly through specialized mechanisms with minimal interference from other dietary factors

Benn, S

The meta-analysis by Tuersun found no significant difference in body weight reduction when comparing the combination therapy to either GLP-1RA monotherapy or SGLT2i monotherapy: this finding challenges the assumption of a synergistic or additive effect on weight loss [15]

doi: 10.1016/j.intimp.2019.105969 28 HelmstdterJKeppelerKAustFKsterLFrenisKFilippouKet al

More specifically, GE2 reduced visceral fat in males on SD, and tended to reduce this fat depot in WD-fed females

And most regulatory bodies, including the U.S