Specific intervention scenarios of GLP-1 on cellular energy economics Treatment of diabetes: correcting the "imbalance of energy distribution" The core pathology of type 2 diabetes is insulin resistance and beta cell function failure, which leads to the imbalance of energy distribution: the intake of glucose by muscle and adipose tissue is reduced, the liver gluconeogenesis is increased, and the levels of glucose and FFA in the blood are increased, forming a vicious cycle of "hyperglycemia hyperlipidemia"
doi: 10.1111/jpi.70005 122 LiuYLiYXiaYLiuKRenLJiYJM
If renal function does reduce, it may be of value to discuss side effects experienced with the patient and reiterate the importance of maintaining adequate fluid intake when unwell
The real goal in the long run is to preserve overall health. If approved in type 1 diabetes, adjunctive therapies could go a long way towards preventing heart and kidney damage and improving wellbeing in the long-term
"Alterations in glutathione levels in Parkinson's disease." Ann Neurol
Alpha-synuclein dimerization in erythrocytes of patients with genetic and non-genetic forms of Parkinsons Disease
