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Cai T, Wagenlehner FM, Mazzoli S, et al

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Since GLP-1 drugs have come to market, supplement companies have championed nutraceutical solutions for weight management

High cortisol also impairs insulin sensitivity and disrupts blood sugar regulation, working directly against the mechanisms that make GLP-1 medications effective

However, these studies are small and need much more follow up work before any conclusions are drawn from it [50]

When combined, fasting and GLP-1 medications can complement each other