Metabolite concentrations were subsequently interquantile range (IQR) filtered and analyzed using univariate ANOVA and t -tests (unpaired, unequal variance assumed) to generate the volcano plots
Persons exposed to once-weekly semaglutide were more likely to be married or living with a partner, had a longer duration of diabetes, higher values of hemoglobin A1c and estimated glomerular filtration rate, and were more likely to use insulin and non-insulin glucose-lowering medicine, and to have diabetic retinopathy
the effect of SBP was recovered by 1828 weeks, and became less significant again after 28 weeks, although this effect was very slight
JAMA Data Brief: GLP-1 receptor agonist use among US adults with type 2 diabetes nearly doubled between 2019 and 2022, primarily driven by semaglutide and dulaglutide
[DOI] [PubMed] [Google Scholar] 98.Christensen, M
Some patients experience mild discomfort at the injection site, temporary flushing or a metallic taste during the infusion