42 deaths occurred in patients with follow-ups, with an SMR (95% CI) of 0.61 (0.44, 0.82)
Common symptoms include: Extreme fatigue that is not relieved by rest Post-exertional malaise: worsening of symptoms after physical or mental activity Sleep problems: unrefreshing sleep, insomnia, or other sleep disturbances Cognitive difficulties: problems with memory, focus, and concentration (often referred to as "brain fog") Muscle or joint pain Headaches Sore throat Tender lymph nodes Dizziness that worsens with moving from lying down or sitting to standing Causes and Risk Factors The exact cause of CFS is unknown, but it is believed to result from a combination of factors: Genetics: A family history of CFS or other autoimmune diseases can increase the risk
In addition to mediating inflammatory reaction and immunity, autophagy is also an important mechanism for clearing excess reactive oxygen species (ROS) to prevent cell damage and death
However, as we mentioned in the introduction, we still need more research to confirm these benefits
The heme oxygenase system: its role in liver inflammation
CBD may increase the amount and activity of antioxidant enzymes 18,19,20 and interrupt the free radical chain reactions 21
