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In the absence of GPR146, impaired adipocyte differentiation and reduced lipolytic capacity together lead to diminished efflux of free fatty acids (FFAs) from adipose tissue

Bertram, S

It is necessary to expand extensive chronic clinical trials to evaluate the long-term safety, efficacy, and optimal dosing of polyphenols, examine gene-diet and microbiota-polyphenol interactions to elucidate inter-individual variability, develop innovative delivery systems to improve bioavailability and facilitate clinical translation, and clarify potential drug interactions and safety in vulnerable populations

10.1016/j.biopha.2020.110408 263 ZhangY.LiX.LuoZ.MaL.ZhuS.WangZ.et al (2020b)

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