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Aquacult Rep 36:102123 Fan Y et al (2024) Natural antioxidants mitigate heavy metal induced reproductive toxicity: prospective mechanisms and biomarkers

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References Leslie SW, Siref LE, Soon-Sutton TL, Khan MAB

The first conclusive evidence for CSCs was published in 1997 [286], and to date CSCs have been isolated from both leukemias and a variety of solid tumors, including breast, brain, pancreatic, prostrate, ovary, and colon cancers [287-293]

Cu ions are bound by proteins like metallothioneins and ceruplasmin, which stops it from catalysing the breakdown of hydroperoxides into free radicals [212, 213]

These results suggested that hypoxia stress may play an initiating or promoting role in the pathogenesis of -syn-related diseases such as PD and DLB