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Hormonal and inflammatory modulatory effects of hesperidin in hyperthyroidism-modeled rats

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Recent multi-segmental magnetic resonance imaging study comparing patients with T2DM and healthy controls have found that patient T2DM group had 40% larger small bowel volume, less small bowel motility postprandially and there were positive associations between small bowel motility and constipation scores ( Conclusion This study identifies distinct expression patterns and functional effects of GLP-1 and GIP in jejunal muscle from obese individuals with and without T2DM

The current FDA commissioner has been supportive of obesity drug development, but political changes are unpredictable