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People who received semaglutide injections during clinical trials achieved a 5.9% weight loss percentage at 3 months and 10.9% at 6 months.* After 6 months, there were reports of individuals with higher BMIs (body mass index) losing 20-30% of their body weight

These findings suggest that GLP-1R signaling remains functional in Bbs5 / mice and could represent a promising therapeutic target for the hyperphagia and obesity associated with BBS