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The analysis did reveal that tolerability may differ among specific BMI classes, since more discontinuations occurred with semaglutide among lower BMI classes, the researchers wrote

People may experience more side effects with semaglutide compared to tirzepatide, according to one study

Its where and how people are getting it

GLP-1 users arent causing a seismic shift in restaurant behavior changes are more gradual and took a couple of years to come about, said Brooks Berrodin, director of Thought Leadership, Foodservice at Circana While it is important for restaurants to adjust to the changing reality, GLP-1s arent yet disrupting the industry. One of the most noticeable shifts is in portion sizes as consumers are no longer looking to super size their orders and instead they are looking for ways to manage the amount they eat and drink, Berrodin explained