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In a large clinical trial for Soliqua, 20% of participants taking Adlyxin alone experienced nausea, compared to 9% of those taking Soliqua

2014 An interactive 3D model rendered from the compound record rotate and explore its structure

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However, because it affects digestion, people should be aware of changes in their bowel habits while taking the medication

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Hills research does suggest that, while the API is a minor cost component compared to the pen in an injectable formulation, the need to dose daily for a higher API load in a pill makes orals pricier to manufacture than injectables, further raising the competitive advantage of manufacturing small molecule alternatives, such as Lillys orforglipron