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Other oral diabetes medications should also be reviewed during this period

INTRODUCTION Melasma is an acquired, chronic, and recurrent form of hypermelanosis, which is characterized by symmetrical brown macules and patches of variable darkness on sun exposed areas of the body, typically occurring on the face (lower cheeks, forehead, nose, and upper lip).[] Though the pathogenesis of melasma is unclear, factors such as genetic makeup, ultraviolet (UV) radiation, pregnancy, and hormonal therapy are known to influence the development of melasma

The long-term phase is about sustaining results, optimizing body composition, and maintaining the metabolic improvements gained during the initial months

However, this side effect is manageable

A genetic baseline option that no SHED tier matches

Patients provided written informed consent prior to collection