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In this regards, SODs are classified into three forms and these include (i) Fe-SOD which is commonly found in prokaryotes and chloroplasts of some plants (ii) Mn-SOD which is present in prokaryotes and mitochondria of eukaryotes and (iii) Cu/Zn-SOD is predominant in eukaryotes and more distributed, localized basically in cytosol but also found in chloroplasts and peroxisomes.25, 26 The various isozymes of SOD are encoded by different genes

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Only case reports report that GLP-1 RAs may improve glucose homeostasis and reduce circulating insulin levels, leading to a gradual improvement in skin manifestations of AN [39]