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Mikdachi and Dunsmoor-Su 2025 in Current Opinion in Obstetrics and Gynecology concluded GLP-1 receptor agonists are consistently the most effective pharmacologic for weight loss in peri and postmenopausal women, while flagging that dedicated randomized trials do not yet exist

Treatment Implications GLP-1 receptor agonists are effective in reducing cardiovascular events and improving metabolic parameters, but (particularly long-term) patient benefit appears greater with surgical intervention

Oral GLP-1 formulations, taken daily, do not require the same timing consideration since the dose is distributed throughout the week

GCLC catalyzes the rate-limiting step of GSH synthesis

Should I stop tirzepatide if side effects feel unbearable during weeks two and three

Use of glucagon-like peptide 1 receptor agonists in eating disorder populations