To gauge improvement, track specific issues you had before, for instance, frequency of mouth sores (which can occur with B deficiencies), or numbness in feet, or level of fatigue on a 10-point scale
If you see both options, choose based on price, supplier reputation, and product testing
doi: 10.2174/157015913666160502153022
doi: 10.1146/annurev.immunol.23.021704.115707 101 WekerleH
Compile an actionable checklist: exercise schedule, toxin-reduction swaps, sleep targets, dietary goals, and supplement review with a clinician
alcohol dehydrogenase and more importantly Acetaldehyde are the issues i took NAC (Jarrows 600 mg sustained release, on amazon) 3X daily for about 10 days prior to having an alcoholic beverage and my reaction (feeling very drunk from 2-3 drinks which lasted hours on end, poor sleep, horribly hungover) was gone