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25.3 Lentigo simplex: this is a small, uniformly pigmented macule clinically indistinguishable from an ephelide

Interestingly, while GLP-1-expressing NTS neurons also project to the ventral striatum [102] and administration of exendin-4 into this brain region reduces food intake and the motivation to obtain a food reward [100, 102], this treatment does not affect ventral striatal dopamine release [103]

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Again, body weight and food intake were monitored once daily in the afternoon