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Practical steps to manage this: Continue taking levothyroxine first thing in the morning on an empty stomach Wait at least 30 to 60 minutes before eating or taking other medications Check TSH levels 6 to 8 weeks after starting Zepbound and after each dose increase Report any return of hypothyroid symptoms to your prescriber promptly Gastrointestinal Side Effects Nausea, diarrhea, constipation, and decreased appetite are the most frequent side effects

Akbari M, Vali M, Rezaei S, Bazmi S, Tabrizi R, Lankarani KB

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