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Moreover, caspase-8 was found to antagonize necroptosis, as evidenced by accelerated necroptosis of erythrocytes in response to caspase-8 inhibition [198]

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This decrease in absorption is hypothesized to be caused via the alkalization of the colonic lumen, resulting in both decreased solubility of Mg 2+ as well as the expression of the TRPM channels (Gommers et al