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In the STEP-4 clinical trials, participants who discontinued the medication began to regain weight within a few months
The mechanism of action centres on mimicking a naturally occurring hormone called GLP-1, which is released from the intestine after eating
Not in a flashy, trend-of-the-moment way, but in a deeper people are truly eating differently kind of way
Hexarelin does this through a calcium/PKC cascade while blunting somatostatin's inhibitory signal, and Ipamorelin is considered more selective because it does not meaningfully raise cortisol or prolactin alongside GH
Incidence (epidemiological)
