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Interestingly, Pycnogenol intake in osteoarthritis patients reduced gene expression of key catabolic and inflammation markers like MMP-3, MMP-13 and IL-1 by more than 50% within knee cartilage (71)

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Die effektivste Form in Studien war die Injektion, allerdings gibt es auch Oralprparate (Kapseln, Tropfen) und transdermale Patches, die sehr gute Bioverfgbarkeit bieten