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A European 2-year multicenter trial observed significant weight regain in patients who discontinued orlistat and switched to placebo compared with those who continued [16]

A higher risk of diabetic retinopathy (DR) associated with semaglutide OW versus placebo was reported in SUSTAIN 6, although this increased risk of DR AEs with semaglutide OW versus comparators was not observed in SUSTAIN 1 to 5 or Japanese trials [58]

Some clients may feel a mild soreness at the injection site, which resolves quickly

Its more of a way to either treat or prevent early disease, not a way to reverse existing liver disease, Lake said

Del Giorno R, Skaper S, Paladini A, Varrassi G, Coaccioli S

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