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FAD is essential for the activity of methylenetetrahydrofolate reductase (MTHFR), an important enzyme in folate metabolism, responsible for converting 5,10-methylenetetrahydrofolate into 5-methyltetrahydrofolate [68]

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In accordance with a previous study, males had higher blood NAD + than females 29 , and the same was true for NADP +

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