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[11] In one crossover study, patients with bipolar disorder on lithium were given either 15 mg or 300 mg of MB daily, and those on the higher dose experienced significantly less depression, suggesting efficacy at that dose, though side effects and long-term safety at such high doses remain concerns

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BIM is an active agent of apoptotic protein, and it has been reported that simvastatin causes expression of BIM, inhibition of ERK protein signals, and the death of apoptotic cells in H1975 cell culture

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Sterile Water for Injection Sterile Water for Injection (USP) is a sterile, nonpyrogenic preparation of water that contains no added substances (no antimicrobial agents, buffers, or other solutes)