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Associated with HU, HDAC gene inhibition produced a more pronounced increase of -globin and HbF ( DNA Methyltransferase 1 is involved in the shutting down of -globin gene after birth and its subsequent production

It also modulates immune responses in the respiratory tract, reducing the production of pro-inflammatory cytokines and alleviating inflammation

doi: 10.1111/j.1524-4725.2005.31086

These results also confirmed the anti-inflammatory and anti-oxidative effects of puerarin in the digestive tract inflammation model

In rare cases, side effects may include allergic reactions or interactions with certain medications

For instance, studies in laboratory rodents have found that dietary omega-3 PUFA deficiency impaired measures of cognitive performance through influencing the dopamine neurotransmitter system in the frontal cortex region of the brain (98)