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(This aligns with the labels gradual escalation to promote tolerability.) When to consider dosage adjustments Dose decisions are medical decisions, but there are common checkpoints to discuss with your clinician: Youve been on your current dose at least 4 weeks, side effects have settled, and your weight trend has flattened despite steady habits

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This is why weekly dosing works: the old dose is still partially active when you inject the new one, creating a steady therapeutic window